Anion Gap calculator
Result
14mmol/L
High AG (>12). Corrected: 14 mmol/L — MUDPILES?
Corrected AG adjusts for hypoalbuminaemia (add 2.5 per 10 g/L below 40).
How to use it
- 1
AG = Na − (Cl + HCO₃). Normal 8–12 mmol/L.
- 2
Correct for albumin. Each 10 g/L below 40: add 2.5 to AG. Hypoalbuminaemia masks HAGMA.
- 3
MUDPILES mnemonic. Methanol, Uraemia, DKA/alcoholic ketoacidosis, Propylene glycol, Isoniazid/iron, Lactate, Ethylene glycol, Salicylates.
When to use it
- Metabolic acidosis work-up
- HAGMA (AG > 12): identify culprit from MUDPILES. NAGMA: FENa, UAG, RTA.
- ICU acid-base
- Calculate delta ratio (ΔAG/ΔHCO₃) to identify mixed disturbances.
- DKA monitoring
- Normalising AG (not glucose) confirms DKA resolution → begin transition to SC insulin.
A reference for clinicians and students, not medical advice. A score supports a decision; it does not make one. Check every result against the patient in front of you and your local protocol.
At a glance
- Specialty
- Critical care
- Inputs
- 4
- Type
- Formula
