Complex venous access in superior vena cava syndrome secondary to gray zone lymphoma, case report

Introduction

Mediastinal gray zone lymphoma (MGZL) is a rare and biologically complex lymphoma with overlapping features of primary mediastinal B-cell lymphoma and classical Hodgkin lymphoma. Bulky mediastinal disease frequently complicates central venous access, particularly in the presence of superior vena cava (SVC) syndrome. Reports addressing optimal vascular access strategies in this setting remain limited.