Cancer medicine
Self-Reported Cancer-Related Cognitive Impairment and Psychosocial Symptom Burden in Survivors of Head and Neck Cancer
By Lin ME, Stenzel J, Delavary D and 4 others.
Abstract
Background
Cancer-related cognitive impairment (CRCI) is an increasingly recognized survivorship concern, yet its prevalence and associated clinical and psychosocial factors among survivors of head and neck cancer (HNC) remain poorly characterized.
Methods
This cross-sectional study recruited survivors of HNC, who were at least 1-year post-diagnosis, from an institutional tumor registry to complete a comprehensive survey. Self-reported cognitive function was assessed using the PROMIS Cognitive Function Short Form 8a, with a T-score < 40 indicating cognitive impairment. Symptom burden was assessed using the EORTC QLQ-HN43, PROMIS short forms, and the Insomnia Severity Index. Social role functioning was assessed using the PROMIS Satisfaction with Participation in Social Roles short form. Multivariable linear and logistic regression examined factors independently associated with self-reported cognitive impairment.