YWHAG overexpression correlates with an immune-desert microenvironment and poor prognosis in laryngeal squamous cell carcinoma

Background

Laryngeal squamous cell carcinoma (LSCC) remains a major cause of cancer-related mortality among head and neck malignancies. The tumor immune microenvironment plays a critical role in determining disease outcome; however, the specific immune cell composition and its prognostic relevance in LSCC have not been fully elucidated.