Cancer medicine
Multi-Center Evaluation of Opioid Administration or Prescription in Pediatric Oncology Patients Using the OMOP CDM
By Feng Y, Yi M, Aftandilian CC and 15 others.
Abstract
Purpose
Opioid use in pediatric oncology is poorly characterized. The primary objective was to describe opioid administration or prescription patterns in pediatric oncology patients.
Methods
In this multi-center retrospective study conducted across three sites, we included patients aged 0-19 years with a malignant neoplastic disease who received their first chemotherapy between January 2019 and March 2024. Data were extracted from each site's Observational Medical Outcomes Partnership Common Data Model. We described patient characteristics based on: (1) first opioid administration or prescription, overall and for each specific opioid; and (2) all opioid administrations or prescriptions, overall and for each specific opioid. We also evaluated variability in opioid and naloxone use.