Chelidonic acid attenuates 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis by modulating oxidative stress and detoxification pathways in Golden Syrian hamsters

Background

Chemoprevention studies using bioactive phytochemicals have emerged as a promising approach for the preliminary evaluation of compounds that inhibit carcinogenesis. Phytochemicals have gained attention as chemopreventive agents due to their antioxidant properties, ability to modulate phase I and II detoxification enzymes. Such studies provide a strong foundation for the development of effective anticancer agents with minimal side effects.