GSDMD Promotes Epithelial-Mesenchymal Transition and Lymph Node Metastasis in Cervical Cancer in vitro and in vivo

Background

Lymph node metastasis (LNM) is a critical determinant of prognosis in cervical cancer (CC). Tumor-associated macrophages (TAMs) and inflammatory signaling within the tumor microenvironment have been implicated in metastatic progression; however, the molecular mechanisms linking inflammation to lymphatic dissemination remain poorly understood.