Journal of Shahrekord University of Medical Sciences
Anti-Addictive Effects of Astragalus Fasciculifolius Extract in a Mouse Stress-Induced Morphine Dependent Model
By Fatemeh Azizi, Nasim Shahrani, Najmeh Asgharzadeh and 5 others.
Abstract
Introduction
Morphine is a potent analgesic with a high potential for addiction. Emerging evidence suggests that natural products may offer therapeutic benefits in addiction management. Therefore, this study aimed to evaluate the effects of Astragalus fasciculifolius extract on morphine-seeking behavior in a mouse model subjected to acute stress. The study also investigated how A. fasciculifolius influences morphine-induced conditioned place preference (CPP) and related biochemical changes in stressed mice.