Machine Perfusion and Oncologic Outcomes After Liver Transplantation for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

Background

Machine perfusion has emerged as a promising strategy to attenuate ischemia–reperfusion injury during liver transplantation (LT). However, its impact on hepatocellular carcinoma (HCC) recurrence and post-transplant oncologic outcomes remains uncertain. We performed a systematic review and meta-analysis evaluating the association between machine perfusion and oncologic outcomes after LT for HCC.