The Effect of Choline on Viability in Prostate Carcinoma Cells: Possible Involvement of Cholinergic Regulation

Background and Purpose: Prostate carcinoma is a frequently encountered tumor, and due to its relatively long survival period, early diagnosis, treatment, and follow-up are crucial in this cancer. Changes in the tumor microenvironment, including neural alterations, have drawn attention to their effects on treatment and prognosis. The mechanism of neural effects, such as acetylcholine (ACh), in prostate cancer is not yet fully elucidated. The aim of this research is to investigate the possible interaction of choline on cell viability in prostate carcinoma cells. The aim of this study to investigate the effects of choline in normal prostate cells and cells of prostate carcinoma.