Fully Automated Segmentation of [ 18 F]FDG and [ 68 Ga]/[ 18 F]PSMA PET/CT Images via Data-Centric Deep Learning

The purpose of this study was to develop and validate lesion identification in oncologic nuclear imaging (LION), an open-source PET-only tumor segmentation pipeline for [18F]FDG and prostate-specific membrane antigen (PSMA)–targeted PET/CT, and to investigate how training data characteristics influence segmentation performance.