Osteosarcopenia Predicts Mortality in Metastatic Prostate Cancer: A Longitudinal Analysis of Opportunistic CT Imaging

Background

/Objectives: Osteoporosis and sarcopenia are associated with fractures, falls, and mortality. In prostate cancer, aging, advanced disease, and androgen deprivation therapy may accelerate concurrent bone and muscle loss. This study characterized longitudinal CT-derived musculoskeletal biomarkers in metastatic prostate cancer and evaluated the association between baseline osteosarcopenia and overall survival.