Circulation Reports
Troponin I Surveillance to Risk-Stratify Early Events After Immune Checkpoint Inhibitor Initiation
By Hiroyuki Fujii, Yuichi Tamura, Masao Daimon and 8 others.
Abstract
Background: Troponin surveillance may facilitate early detection of immune checkpoint inhibitor (ICI)-associated myocarditis, but mild elevations and baseline abnormalities complicate interpretation. We assessed early post-ICI troponin I (TnI) dynamics and the performance characteristics of clinically applicable peak TnI thresholds within 3 months of ICI initiation.
Keywords
- Cancer Immunotherapy and Biomarkers
- Immune system
- Troponin
- Pembrolizumab
- Immune checkpoint
- Immunotherapy
- Myocarditis
- Open access
Source
Published in Circulation Reports. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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