Analysis of ICG Arrival Time in Relation to ICG Lymphography Stage and Lymphoscintigraphy Severity Stage for Upper Limb Lymphedema Diagnosis: A Retrospective Observational Study

Background

Indocyanine green lymphography (ICG L) and lymphoscintigraphy (LS) are widely used to stage breast cancer–related upper limb lymphedema (BCRL); however, both are primarily read qualitatively. We evaluated whether a pragmatic ICG time to axilla metric (elapsed time from hand injection to axillary visualization) correlates with MD Anderson (MDACC) ICG L stage and LS severity.