Aminolevulinic acid photodynamic therapy for extensive genital extramammary Paget disease in older patients: A retrospective clinical case series

Background

Extramammary Paget disease (EMPD) involving the genital and anogenital region is difficult to manage when lesions are extensive, chronic, or located across functionally sensitive sites. In older patients with diabetes, cardiovascular disease, or advanced local involvement, wide excision may lead to considerable perioperative burden, delayed healing, and anatomical impairment.