Recommendations for the management of functional dyspepsia from the SEGHNP working group on motility and functional gastrointestinal disorders

Functional dyspepsia (FD) is a functional gastrointestinal disorder that affects a significant number of patients, especially adolescents. Diagnosis is often challenging on account of both the differential diagnosis with organic diseases and the overlap with other disorders involving the gut-brain axis. Furthermore, there is a lack of scientific evidence on the effectiveness of the different treatments. As a result, there is evidence of substantial heterogeneity in the management of these patients due, in part, to the absence of clinical practice guidelines on this disease.

A group was formed that consisted of 19 members of the working group on motility and functional gastrointestinal disorders (FGIDS) of the SEGHNP. The group defined 27 clinical questions regarding the management of FD. After a review of the literature and two rounds of anonymous voting, the group elaborated a document summarizing the current evidence and offering recommendations.

The group produced a summary of the evidence and developed 27 recommendations on FD.

We developed an algorithm with the aim of standardizing the management of patients with FD.

Published by Anales de pediatria, 2025. The guideline itself is at the source linked here.

doi.org/10.1016/j.anpede.2025.503860