Quality measures in the design, conduct, and reporting of endoscopic research.
Published by American Society for Gastrointestinal Endoscopy (ASGE) [2-4] · Expert opinion and group consensus [2, 5]
Summary
AI-generatedThis guideline from the ASGE proposes 9 quality measures designed to improve the design, conduct, and reporting of endoscopic research [1]. Developed by a joint task force via group consensus and systematic literature searches [2], it establishes a framework covering sample size calculation, patient selection, outcome definitions, data integrity, blinding, trial oversight, equity, and conflict disclosures [1, 2, 6, 8].
Key Takeaways
- 1High-quality clinical investigation in endoscopy requires rigorous methodology and transparent reporting.
- 2The ASGE Quality Assurance in Endoscopy and Research Committees established these 9 quality measures to provide a practical, structured framework.
- 3While not all measures are evidence-based, they rely on expert opinion, logic, and consensus to optimize research design and integrity.
- 4Applying an equity lens across the entire research continuum (study choice, patient selection, and AI algorithm development) is highly encouraged to produce fair and generalizable results.
What's New in This Version
This document represents the first version (v1) of these quality measures, prioritizing indicators judged to be reasonably practical and achievable. Content is expected to evolve in future versions based on feedback from endoscopic investigators and a changing evidence base.
Key Recommendations
Quality measures
- 1
The study adheres to published reporting guidelines
Unanimous consensusEvidence: Expert opinion and literature reviewReporting - 2
The sample size is calculated a priori and according to established principles
Unanimous consensusEvidence: Expert opinion and literature reviewDesign - 3
The study sample reflects the patient population to which the results will apply
Unanimous consensusEvidence: Expert opinion and literature reviewDesign - 4
Study outcomes and exposures or interventions are clearly defined before study implementation, and are as objective as possible
Unanimous consensusEvidence: Expert opinion and literature reviewDesign - 5
Data integrity is ensured throughout the data acquisition and verification processes
Unanimous consensusEvidence: Expert opinion and literature reviewConduct - 6
Blinding in randomized trials is maintained to the greatest extent possible
Unanimous consensusEvidence: Expert opinion and literature reviewConduct - 7
Randomized trials are conducted under the oversight of an independent data and safety review committee
Unanimous consensusEvidence: Expert opinion and literature reviewConduct - 8
The research is designed and conducted inclusively and equitably
Unanimous consensusEvidence: Expert opinion and literature reviewDesign / Conduct - 9
Commercial and intellectual conflicts of interest are disclosed and managed
Unanimous consensusEvidence: Expert opinion and literature reviewReporting / Disclosure
Scope & Objectives
Clinical Topic
Quality measures in endoscopic research [1, 2]
Objectives
To propose quality measures that aim to improve the overall quality, rigor, and generalizability of endoscopy and endoscopy-related research [1]
Target Patient Population
Patients undergoing endoscopic procedures [1, 6]
Target Providers
Patient Criteria & Setting
Therapeutic Area
Gastroenterology [2, 3]Guideline Scope
Evidence Grading
System: Expert opinion and group consensus [2, 5]
Safety & Contraindications
Monitoring Guidance
Central monitoring of incoming data to identify trends, duplicate data entry for minimizing risk of errors, and auditing a percentage of medical records for data accuracy and quality assurance [10].
Authors & Contributors
Guideline Features
Learning Context
Difficulty
advanced
Learning Paths