European Association for the Study of the Liver
EASL Clinical Practice Guidelines on the management of extrahepatic cholangiocarcinoma
Abstract
Recent years have witnessed significant advances in the imaging, molecular profiling, and systemic treatment of cholangiocarcinoma (CCA). Despite this progress, the early detection, precise classification, and effective management of CCA remain challenging. Owing to recent developments and the significant differences in CCA subtypes, EASL commissioned a panel of experts to draft evidence-based recommendations on the management of extrahepatic CCA, comprising distal and perihilar CCA. Particular attention is given to the need for accurate classification systems, the integration of emerging molecular insights, and practical strategies for diagnosis and treatment that reflect real-world clinical scenarios.
Source and rights
Published by Journal of hepatology, 2025. The guideline itself is at the source linked here.
Prognia summarises this guideline for reference and education. It is not medical advice. Always check the official guideline and current local protocols before acting on it.
At a glance
- Organisation
- European Association for the Study of the Liver
- Published
- 2025
- Applies to
- 🇪🇺 Europe
- Scope
- Regional
- Journal
- Journal of hepatology
- PubMed
- 40348685









