Chinese expert consensus on clinical practice of chronic hepatitis B functional (clinical) cure

Chronic hepatitis B functional (clinical) cure is currently an important therapeutic endpoint, which significantly reduces the incidence risk of cirrhosis and liver cancer. This expert consensus focuses on key clinical issues on the basis of previous studies, systematically elaborates population stratification and stepwise treatment strategies based on patient characteristics, consolidation therapy, relapse management, long-term monitoring after serum HBsAg clearance, and optimal management for patients who have not achieved the cure goal, and formulates suitable clinical guidance recommendations tailored to the characteristics of Chinese patients, providing scientific evidence and decision-making pathways so as to further standardize and guide the practice of functional (clinical) cure of chronic hepatitis B in China.