Carboplatin Dose (Calvert Formula) calculator
Result
475mg
Carboplatin dose for AUC 5
Calvert formula: Dose (mg) = AUC × (GFR + 25). Cap GFR at 125 mL/min per Chatelut/ESMO recommendations.
How to use it
- 1
GFR: use Cockcroft-Gault or 24h urine. EDTA-GFR or Cockcroft-Gault acceptable. Some centres cap at 125 mL/min.
- 2
AUC target from protocol. Most common: AUC 5 with paclitaxel (NSCLC, ovarian). AUC 6 may be used in fit patients.
- 3
Calvert formula. Dose (mg) = AUC × (GFR + 25).
When to use it
- Carboplatin-containing regimens
- NSCLC, ovarian, lung SCLC, testicular cancer, breast cancer.
- Dose reduction in renal impairment
- GFR drives dose — automatic reduction in CKD without separate adjustment table.
- Protocol verification
- Always cross-check calculated dose with oncology pharmacist and the specific protocol.
A reference for clinicians and students, not medical advice. A score supports a decision; it does not make one. Check every result against the patient in front of you and your local protocol.
At a glance
- Specialty
- Oncology
- Inputs
- 2
- Type
- Formula
