medRxiv
Stage-Specific Associations of Automated RPR With Treponema pallidum qPCR Positivity and Cycle Threshold in Early Symptomatic Syphilis: A Multicenter Study Using Specimens Collected During Routine Care
By Kasamatsu, A., Ohama, Y., Tomo, Y. and 6 others.
Abstract
Background
Treponema pallidum quantitative polymerase chain reaction (qPCR) positivity and cycle threshold (Ct) by rapid plasma reagin (RPR), disease stage, and other characteristics are poorly characterized in routine-care specimens, leaving it unclear when qPCR of such specimens is informative for diagnosis.
