Proceedings
Comparison of Mitomycin-C with Normal Saline in preventing Synechiae formation in patients undergoing Endoscopic Sinus Surgery
By Muhammad Jamil, Wajih ud Din Shinwari, Sadaf Riffat Mustafa and 3 others.
Abstract
Background
Chronic rhinosinusitis (CRS) is a prevalent condition affecting 5% to 12% of the population, often necessitating endoscopic sinus surgery (ESS) for treatment. Postoperative synechiae formation is a common complication of ESS, potentially leading to recurrent infections and impaired healing. Mitomycin-C (MMC), an antineoplastic agent known for its anti-fibrotic properties, has been proposed as a preventive agent against synechiae formation. .
