Photodiagnosis and Photodynamic Therapy
Phenalenone-based photosensitizers for antimicrobial photodynamic inactivation of methicillin-sensitive and methicillin-resistant
By Xingmei Hu, Xiaohan Jin, Chunbao Tian and 9 others.
Abstract
Background and objective: Antimicrobial photodynamic therapy (aPDT) relies on activation of a photosensitizer by light in the presence of oxygen, leading to reactive oxygen species formation. Here, a phenalenone derivative series was examined to find green-light-responsive compounds for photodynamic inactivation of methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA).