Ultrasound-guided foam sclerotherapy using physician-compounded foam: Position statement from the American vein and lymphatic society

Background: Chronic venous disease has a major impact on the quality of life of millions of patients. Large randomized controlled trials have established ultrasound-guided foam sclerotherapy (UGFS) as a safe and effective treatment option for both saphenous vein insufficiency and tributary disease. Ultrasound guidance is a critical component of sclerotherapy of non-visible veins.Method: An expert panel of the American Vein and Lymphatic Society (AVLS) was convened to review the literature and write a Position Statement with recommendations for the use of UGFS with physician-compounded foam for patients with venous insufficiency.Result: Consensus recommendations from the expert panel highlight the advantages and safety of high-quality physician-compounded foam. These recommendations were reviewed, edited and approved by the Guidelines Committee of the AVLS.Conclusion: UGFS with in-office, physician-compounded foam is a safe primary treatment option for varicose, tributary, and truncal veins of the lower extremities and is an important adjunct therapy for tributary disease following or concomitant to endovenous ablation procedures.

Published by Phlebology, 2025. The guideline itself is at the source linked here.

doi.org/10.1177/02683555241309808