Sinonasal malignancy: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up

• The CPG provides key recommendations and algorithms for managing SMs, excluding mucosal melanoma and soft-tissue sarcomas. • The guideline covers diagnosis, staging, risk assessment, treatment and disease monitoring. • Technological advancements in treatment with RT are discussed with a special focus on particle therapy. • Surgical indications for open and transnasal endoscopic surgery are provided. • Neoadjuvant chemotherapy in high-grade, locally advanced SMs helps to select subjects for conservative treatments.