Expert opinion-based recommendations promoted by GTIPO-SEDAR to optimize the therapeutic management of intra-abdominal candidiasis

Intra-abdominal candidiasis (IAC) is a highly prevalent infectious syndrome and a significant cause of mortality in Intensive Care Units (ICUs). The Working Group on Perioperative Infections of the Spanish Society of Anesthesiology, Resuscitation, and Pain Management (GTIPO-SEDAR) has promoted the development of recommendations based on the experience of a multidisciplinary panel of experts from various medical specialties, aiming to optimize the diagnosis and treatment of severe infectious processes such as IAC. These recommendations have been formulated through a rigorous critical appraisal of the currently available scientific evidence. This document provides guidance for optimizing the therapeutic approach to IAC, incorporating the latest findings in microbiology, recent therapeutic advances, pharmacokinetic and pharmacodynamic considerations in critically ill patients with intra-abdominal candidiasis, special therapeutic considerations for patients undergoing extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapies (CRRT), the appropriateness of empirical versus targeted therapy, and strategies for improving and reducing the duration of treatment.

Published by Revista espanola de anestesiologia y reanimacion, 2025. The guideline itself is at the source linked here.

doi.org/10.1016/j.redare.2025.501916