Critical Gaps in the Scientific Basis for Electronic Cigarette Regulation: An American College of Chest Physicians Research Statement

The 2009 Family Smoking Prevention and Tobacco Control Act granted the US Food and Drug Administration regulatory authority over tobacco products, extended to include electronic cigarettes (ECs) in 2016. Regulatory science informs potential market restrictions based on the population health standard. The American College of Chest Physicians (CHEST) Tobacco/Vaping Work Group is charged with prioritizing tobacco-related advocacy. To identify critical gaps in the science guiding EC regulation, we undertook a systematic exploration of existing evidence to develop future research recommendations.