Clinical practice guidelines for standardized management of stillbirth (2026 edition)

Stillbirth is one of the most common adverse pregnancy outcomes. It not only causes physical and psychological trauma to pregnant and puerperal women but also imposes heavy family and socioeconomic burdens. Standardized clinical management of stillbirth is crucial for improving the quality of the birth population. Such management should be based on a multidisciplinary collaborative diagnosis and treatment model, covering a complete pathway including high-risk factor screening, risk stratification and early warning, whole-pregnancy monitoring, and intervention in subsequent pregnancies. Accordingly, this guideline was jointly developed by the Fetal Medicine Group of the Chinese Society of Perinatal Medicine (Chinese Medical Association), the National Obstetric Quality Control Center, and the National Clinical Research Center for Obstetric and Gynecologic Diseases of China. We followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system and international reporting standards for practice guidelines. A multidisciplinary expert team was established to systematically review evidence on 32 key clinical questions in China and formulate evidence-based recommendations, so as to provide guidance for the standardized management of stillbirth in China. This guideline aims to provide a knowledge framework and practical guidance for primary healthcare professionals, obstetricians, clinical pharmacists, nurses at all levels of medical institutions, as well as pregnant women and their families.

死胎是最常见的不良妊娠结局之一，除对孕产妇造成身心创伤，还会带来沉重的家庭及社会经济负担，规范死胎的临床管理对提高出生人口质量至关重要。规范的死胎管理应依托多学科协作诊疗模式，包含高危因素筛查、风险分层预警、妊娠期全程监测及再次妊娠干预的完整管理路径。为此，由中华医学会围产医学分会胎儿医学组、国家产科专业医疗质量控制中心、国家妇产疾病临床医学研究中心联合发起制订了本指南，遵循证据推荐分级的评估、制订与评价系统和国际实践指南报告标准，组建多学科专家团队，针对我国临床实践最关注的32个问题进行了循证医学证据综合，并形成了推荐意见，从而为我国死胎的规范化管理提供指引。本指南旨在为基层医疗专业人员、各级医疗机构的产科临床医师、临床药师和护师，以及孕产妇及其家属提供死胎范化管理的知识体系和实践指导。.