Clinical practice guideline on the optimal radiotherapeutic management of brain metastases

An evidence-based clinical practice guideline on the optimal radiotherapeutic management of single and multiple brain metastases was developed.

A systematic review and meta-analysis was performed. The Supportive Care Guidelines Group formulated clinical recommendations based on their interpretation of the evidence. External review of the report by Ontario practitioners was obtained through a mailed survey, and final approval was obtained from Cancer Care Ontario's Practice Guidelines Coordinating Committee (PGCC).