European Academy of Neurology
EAN 2024 Guideline on the Diagnostic Approach to Oligo/Asymptomatic HyperCKemia
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Abstract
Recent epidemiological studies on the general population reveal that up to 1.3% have oligo/asymptomatic hyperCKemia.
This guideline aims to provide updated, evidence-based recommendations on investigating persons older than 18 years.
The guideline followed EAN standard operating procedures and was developed according to the GRADE methodology. Fourteen neuromuscular experts from the EAN neuromuscular group were joined by a methodologist and a patient representative. There are two types of recommendations: evidence-based recommendations, based on published studies, and consensus statements if the quality of evidence is poor.
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