A methodological guideline for consciousness assessment via neural electrophysiological activity

Physiological, pharmacological, and pathological alterations of consciousness provide critical windows into its neural substrates. Given the inherent complexity and multidimensionality of consciousness, defining quantitative, dynamic signatures of neural activity, and translating them into clinically applicable tools remains challenge. This study aimed to build an electroencephalography (EEG)-based methodological guideline for clinical consciousness assessment.