| Pramox HC CreamCombination | 🇨🇦Canada | 1 % + 1 % | Cream | Marketed | Dermtek Pharma INC |
| Pramox HC LotionCombination | 🇨🇦Canada | 1 % + 1 % | Lotion | Marketed | Dermtek Pharma INC |
| Proctodan-HC OintmentCombination | 🇨🇦Canada | 0.5 % + 1 % + 0.5 % | Ointment | Marketed | Odan Laboratoriesltd |
| Proctodan-HC SuppositoriesCombination | 🇨🇦Canada | 10 MG + 20 MG + 10 MG | Suppository | Marketed | Odan Laboratoriesltd |
| Anusol Plus OintmentCombination | 🇨🇦Canada | 1 % + 0.5 % | Ointment | Marketed | Church & Dwight Canada Corp |
| Polysporin Itch ReliefCombination | 🇨🇦Canada | 1 % / W/V + 0.1 % / W/V | Lotion | Marketed | Kenvue Canada INC. |
| Anusol Plus SuppositoriesCombination | 🇨🇦Canada | 20 MG + 10 MG | Suppository | Marketed | Church & Dwight Canada Corp |
| Preparation H CreamCombination | 🇨🇦Canada | 14.45 % / W/W + 0.25 % / W/W + 1 % / W/W + 15 % / W/W | Cream | Authorised | Haleon Canada Ulc |
| Aveeno Anti-Itch LotionCombination | 🇨🇦Canada | 3 % / W/W + 1 % / W/W | Lotion | Marketed | Kenvue Canada INC. |
| Gold Bond Anti-Itch LotionCombination | 🇨🇦Canada | 5 % / W/W + 0.5 % / W/W + 1 % / W/W | Lotion | Marketed | Sanofi Consumer Health INC |
| Gold Bond Medicated Anti-Itch CreamCombination | 🇨🇦Canada | 1 % / W/W + 1 % / W/W | Cream | Marketed | Sanofi Consumer Health INC |
| Itch Relief Moisturizing Cream | 🇨🇦Canada | 1 % / W/W | Cream | Marketed | Cerave Canada |
| Itch Relief Moisturizing Lotion | 🇨🇦Canada | 1 % | Lotion | Marketed | Cerave Canada |
| Anodan-PlusCombination | 🇨🇦Canada | 20 MG + 10 MG | Suppository | Authorised | Odan Laboratoriesltd |
| Anodan-Plus OintmentCombination | 🇨🇦Canada | 1 % + 0.5 % | Ointment | Authorised | Odan Laboratoriesltd |
| Hemorrhoidal Ointment with Anesthetic for Extra Pain ReliefCombination | 🇨🇦Canada | 1 % / W/W + 0.5 % / W/W | Ointment | Authorised | Cellchem Pharmaceuticals INC. |
| Itch Relief LotionCombination | 🇨🇦Canada | 1 % / W/V + 0.1 % / W/V | Lotion | Authorised | Cellchem Pharmaceuticals INC. |
| Sarna Calm + Cool Anti-Itch LotionCombination | 🇨🇦Canada | 0.5 % / W/W + 1 % / W/W | Lotion | Authorised | Crown Laboratories INC. |
| Sarna Sensitive Anti-Itch Lotion | 🇨🇦Canada | 1 % / W/W | Lotion | Authorised | Crown Laboratories INC. |
| Tucks Triple Relief Hemorrhoidal CreamCombination | 🇨🇦Canada | 15 % / W/W + 0.25 % / W/W + 1 % / W/W + 16 % / W/W | Cream | Authorised | Blistex Corporation |
| Proctofoam-HCCombination | 🇨🇦Canada | 1 % + 1 % | Aerosol | Not marketed | Duchesnay INC |
| Anuzinc HC PlusCombination | 🇨🇦Canada | 10 MG + 20 MG + 10 MG | Suppository | Not marketed | Laboratoires Confab INC |
| Hemorrhoid OintmentCombination | 🇨🇦Canada | 1 % + 0.5 % | Ointment | Not marketed | Jamp Pharma Corporation |
| PramegelCombination | 🇨🇦Canada | 0.5 % + 1.0 % | Gel | Cancelled | Valeant Canada LP / Valeant Canada S.E.C. |
| Tronothane Pramoxine HCL CRM 1% USP | 🇨🇦Canada | 1 % | Cream | Cancelled | Abbott Laboratories, Limited |