Mention Two Drugs. Osler Checks.
Name two or more medications in any question and Osler automatically resolves them via RxNorm, pulls the known interactions and grades their severity — no separate tool, no form to fill.
Can I add ibuprofen for a patient on warfarin after his NSTEMI?
Checked automatically — no separate tool, no form
The problem
Interaction Checks Live in Another Tab
Traditional interaction checking is a separate tool with a separate form — which makes it the step that gets skipped under time pressure.
- 1
The tool is elsewhere
Question in one window, interaction checker in another. Every context switch is a chance the check never happens at all.
- 2
Forms don’t understand questions
Classic checkers want exact drug names typed into exact fields. Clinical questions don’t arrive that way.
- 3
Every alert shouts equally
When trivial and dangerous interactions look the same in a flat list, alert fatigue buries the one that matters.
Automatic detection
No Form. No Separate Tool.
Name two or more drugs anywhere in a question and Osler detects them automatically, resolves each to a precise concept via RxNorm — the US National Library of Medicine’s drug terminology — and pulls the known interactions.
- Detection happens inside the conversation
- Brand and generic names resolved via RxNorm
- Works in natural phrasing, not fixed fields
- The check runs without being asked
Your question
Can I add ibuprofen for a patient on warfarin?
Severity triage
Serious Warnings Rise to the Top
Every interaction is normalized to high, moderate or low severity. High-severity interactions are promoted to the top of the sources with a red warning banner — and they are never trimmed from the results.
- Three severity levels: high, moderate, low
- High severity flagged with a red warning banner
- Promoted above every other source
- Never buried, never trimmed from results
Interactions found · 3
Simvastatin + Amlodipine
Raised simvastatin exposure — myopathy risk
Lisinopril + Metformin
May enhance the glucose-lowering effect
Warfarin + Ibuprofen
Serious gastrointestinal bleeding risk
Normalized to high · moderate · low — the serious one leads
In context
Interactions Beside the Evidence
The interaction result sits inside the same cited answer as the guideline recommendations and drug labels it relates to — one conversation and one evidence trail, instead of findings scattered across tools.
- Same answer as guideline and label sources
- Citations on the surrounding claims
- Follow-up questions keep the context
- One conversation instead of three tools
One cited answer
In AF patients on warfarin, avoid adding an NSAID1; if unavoidable, co-prescribe a PPI23 and recheck the INR within 3–5 days4.
Interactions, guidelines and labels — one evidence trail
Standalone Checker. In-Conversation Safety.
The same check, moved to where the question is actually asked.
Separate checker tool
- Open a separate interaction checker
- Type exact names into fixed fields
- Ambiguous names, ambiguous results
- A flat list where everything looks urgent
- Serious alerts lost mid-list
- Results detached from the clinical question
With Osler
- Checking happens automatically in the chat
- Drugs detected in your natural question
- Each drug resolved precisely via RxNorm
- High, moderate and low — triaged for you
- High severity promoted with a red warning
- Interactions inside the same cited answer
From Question To Warning
The interaction check follows your question — you never leave the conversation.
- 1
Ask naturally
“Can I add ibuprofen for a patient on warfarin?” — a question, not a form.
- 2
Osler resolves
Both drugs are detected in your phrasing and resolved to precise RxNorm concepts.
- 3
Severity is graded
Known interactions come back normalized to high, moderate or low severity.
- 4
The warning leads
A high-severity interaction opens the answer with a red banner — before anything else.
Connected to the Prognia ecosystem
Where the Check Fits the Ecosystem
Osler checks inside the conversation; the Prognia drug directories carry the reference detail.
Grounded in Public Drug Data
The national drug databases behind Osler’s interaction checks.
Questions about Drug Interactions
Safety That Doesn’t Wait to Be Asked.
Mention the drugs; Osler runs the check — resolved via RxNorm, triaged by severity, serious warnings first. Start free.
Free plan included · No credit card required