MASCC Score calculator
Result
21/26
Low risk (≥21) — oral antibiotics, possible outpatient
How to use it
- 1
MASCC ≥ 21 = low risk. Complication rate ~6%, mortality ~1%. Oral ciprofloxacin + amoxicillin-clavulanate.
- 2
High risk: hospitalise immediately. IV pip-tazo or carbapenem (if prior ESBL/Pseudomonas); add antifungal if >7d neutropenia.
- 3
G-CSF not routinely indicated. MASCC does not incorporate G-CSF — use ASCO/EORTC guidelines for prophylaxis.
When to use it
- Febrile neutropenia (ANC < 0.5 × 10⁹/L + temp ≥38.3°C once or ≥38°C × 1h)
- Oncology emergency — MASCC within 1 hour of presentation.
- Outpatient treatment eligibility
- MASCC ≥21 + no organ dysfunction + reliable patient: outpatient oral regimen.
- Haematological malignancy
- AML/SCT patients almost always high risk regardless of MASCC.
A reference for clinicians and students, not medical advice. A score supports a decision; it does not make one. Check every result against the patient in front of you and your local protocol.
At a glance
- Specialty
- Infectious diseases
- Inputs
- 7
- Type
- Points score








