Test-bolus peak attenuation for predicting aortic enhancement in coronary computed tomography angiography: an exploratory subgroup analysis

Background

Adequate intravascular enhancement is essential for accurate coronary computed tomography angiography (CCTA) evaluation; however, conventional empirical contrast protocols often result in significant variability in enhancement because they do not account for individual physiological differences. Test-bolus techniques represent a potential approach for individualized contrast delivery; however, their precise quantitative relationship with final vascular enhancement requires further clarification. This study aimed to investigate the quantitative association between test-bolus peak attenuation and final aortic enhancement (FAE) in CCTA and to describe subgroup variations based on body mass index (BMI) and cardiac output (CO).