Journal of inflammation research
Integrative Transcriptomic and Genetic Analysis Prioritizes IRF1 as a Candidate Regulatory Gene Associated with Ulcerative Colitis
By Wang Y, Chen Y and Wu H.
Abstract
Background
Ulcerative colitis (UC) is a chronic inflammatory bowel disease with a complex and incompletely understood pathogenesis. This study aimed to prioritize candidate genes associated with UC and characterize their potential genetic and immune-related molecular context using an integrative transcriptomic and genetic framework.
