1H NMR-Based Metabolomics Coupled With Molecular Docking to Explore the Anti-NAFLD Effects of Astragalus Radix and Dioscoreae Rhizoma Herb Pair

Introduction

Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by lipid accumulation in hepatocytes. Our previous study demonstrated that the herbal pair (HS) of Astragalus Radix (HQ) and Dioscoreae Rhizoma (SY) reduces blood lipids and improves hepatic lipid metabolism in high-fat diet-fed mice.