Frontiers in psychiatry
The anxiolytic effect of dexmedetomidine in adult perioperative patients: a systematic review with meta-analysis of randomized controlled trials
By Yang K, Cui JZ, Wang WJ and 1 others.
Abstract
Background
Perioperative anxiety in adults is common and impairs postoperative recovery. The use of dexmedetomidine during perioperative procedures is increasing, but evidence on its effects on anxiety-related outcomes remains to be systematically synthesized.
Methods
This systematic review was based on searches of PubMed, Embase, Web of Science, MEDLINE, and the Cochrane Library from database inception through May 4, 2026. Eligible studies were randomized controlled trials evaluating perioperative dexmedetomidine in adults and reporting quantitative anxiety outcomes.
