Frontiers in immunology
Early monocyte subset signatures predict outcomes in unvaccinated COVID-19 patients
By Oliveira FMS, Caetano MMM, de Oliveira LL and 7 others.
Abstract
Introduction
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized by complex immune responses, with monocytes playing a central role in disease pathogenesis.
Objective
This study aimed to evaluate the profiles of monocytes and their receptor expression during the first week of hospitalization in unvaccinated patients with COVID-19, stratified by clinical outcome: discharged or deceased.