Frontiers in cellular and infection microbiology
Genomic characterization of a mobile-element-associated resistance island in trimethoprim-sulfamethoxazole-resistant Stenotrophomonas maltophilia isolates sharing the same PFGE genotype
By Altan G, Rakıcı E, Dündar D and 1 others.
Abstract
Background
Stenotrophomonas maltophilia is an opportunistic nosocomial pathogen with intrinsic multidrug resistance and limited therapeutic options. This study integrated phenotypic susceptibility testing, targeted molecular screening, PFGE and short-read whole-genome sequencing (WGS) to characterize resistance determinants and their local genomic context in clinical-culture isolates.
