Whole-genome analysis of mumps virus genotype F in Shandong, China (2006-2018)

Introduction

Despite the introduction of mumps-containing vaccines into the routine immunization program in 2008, mumps incidence in Shandong Province, China, declined but remained substantially higher than that of measles and rubella, and above WHO elimination thresholds, raising the possibility of whether genetic evolution of circulating strains has contributed to this phenomenon. To address, we compared mumps viruses isolated pre-vaccine (2006-2007) and a decade after rollout (2018).