Health science reports
Impact of Sickle Cell Hemoglobin Genotypes on Clinical Outcomes Among Plasmodium falciparum Malaria Patients in Luanda, Angola
By Sebastião CS, Ekundi-Valentim E, Cassinela E and 1 others.
Abstract
Background
Sickle cell anemia (SCA) may influence malaria susceptibility and clinical outcomes in endemic regions. However, the interaction between hemoglobin genotypes and malaria severity remain poorly defined in endemic African settings, particulary in Angola, where SCA and malaria impose a substantial public health burden. Herein, we investigate associations between hemoglobin genotypes and clinical outcomes among malaria patients.