JK Science
IgA Nephropathy in Hansen’s Disease with Bizarre Reaction Pattern: A Clinical Uncertainty
By Mridula Thangaraj, Joseph Neha Mariam, Devi Sudhesshna and 1 others.
Abstract
Hansen’s disease is a chronic infectious disease with varied systemic manifestations. Renal involvement is well recognized in Hansen’s disease; however, biopsy-proven primary IgA nephropathy is exceptionally rare. Most reported IgA-associated glomerular lesions in leprosy represent IgA-dominant infection-related glomerulonephritis rather than primary IgA nephropathy. Only isolated biopsy-proven cases have been reported, underscoring the rarity of the present case. We report a 40-year-old man with lepromatous leprosy complicated by IgA nephropathy, whose clinical course was further aggravated by a bizarre noduloulcerative erythema nodosum leprosum (ENL) reaction following treatment non-adherence. This case emphasizes the importance of routine renal screening, multidisciplinary management, and strict treatment adherence in multibacillary leprosy.
Keywords
- Leprosy Research and Treatment
- Open access
Source
Published in JK Science. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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