Frequency of functional outcome and predictors of mortality in patients with tuberculous meningitis at tertiary care hospital Karachi

Background

Tuberculous meningitis is a severe form of extrapulmonary tuberculosis associated with significant neurological disability and mortality. To determine the frequency of functional outcome and predictors of mortality in patients presenting with tuberculous meningitis at Tertiary Care Hospital, Karachi. Material and Methods: This descriptive, longitudinal study was carried out in the Department of Neurology, Jinnah Postgraduate Medical Centre (JPMC), Karachi from February 2026 to July 2026. All patients with tuberculous meningitis were recruited using a non-probability consecutive sampling method. Functional outcomes were evaluated after admission at 90 days with the modified Rankin Scale [mRS] of which good functional outcome was considered as mRS ≤2 and poor functional outcome as mRS 3–6. British Medical Research Council (BMRC) staging system was used. A p-value ≤0.05 was considered statistically significant.