Acta Neurologica Indonesia
Prognostic Value of Mean Platelet Volume in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
By Mary Christina Elsa, David Adinugraha Wijaya, Billy Susanto and 1 others.
Abstract
Introduction
Acute ischemic stroke (AIS), a significant public health concern, causes severe functional impairments. Mean platelet volume (MPV), a marker of platelet activity, is associated with increased platelet aggregation and elevated thromboxane-A2 and β-thromboglobulin levels, factors linked to heightened stroke risk and potentially its severity. This review aims to evaluate the prognostic value of MPV in predicting functional outcome in acute ischemic stroke patients.