Pain research & management
Iron-Sensitive MRI Reveals Individual Differences in Pain Modulation Rather Than Categorical Markers in Chronic Pain and Migraine
By Ydlibi O, Salehi Ravesh M, Bernerth F and 4 others.
Abstract
Objective
To determine whether regional iron levels are associated with endogenous pain-inhibitory function and whether iron-sensitive MRI techniques, quantitative magnetic susceptibility (QSM) and R 2 ∗ mapping capture differences in midbrain iron content in the globus pallidus (GP), periaqueductal grey (PAG), and red nucleus (RN) across chronic pain (CP), migraineurs (M), and healthy volunteers (HV).
