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East African Journal of Neurological Sciences
By Richard Houeze, Richmine Covi, Alexandre Faton and 10 others.
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Neurodegenerative diseases, such as Parkinson's disease (PD), occupy a central place in global public health. The impact of neuropsychiatric disorders like depression and anxiety on a patient's quality of life is well-documented. However, they are under-identified in Africa and Benin due to cultural taboos and limited access to mental health services.
To evaluate the prevalence of depressive disorders in Parkinson's disease patients at the University Neurology Clinic of the National University Teaching Hospital Hubert Koutoukou Maga in Cotonou in 2024.
Patients were retrospectively identified from records between 2015 and 2024 and then assessed cross-sectionally in 2024. The Hospital Anxiety and Depression Scale (HADS) was used to differentiate depressive disorders, alongside a range of general and PD-related clinical characteristics.
A total of 122 cases of Parkinson's disease (PD) were identified, and 42 were included in the study, comprising 36 men and 6 women with a mean age of 59.69 ± 12.18 years. Depression was found in 30.95% of PD patients, with 21.43% experiencing mild depression, 7.14% moderate depression, and 2.38% severe depression. Factors associated with depression included non-motor symptoms, advanced disease stage according to the Hysterical & Young (H&Y) classification, loss of independence, and impairment in all dimensions of quality of life (except social support).
This study revealed a significant prevalence of depressive disorders in Parkinson's disease patients in our region, highlighting their considerable impact on patients' quality of life. These results advocate for a multidisciplinary approach to improve their quality of life.
Published in East African Journal of Neurological Sciences. The abstract is shown as published and remains the work of its authors; read the full article at the source.
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