Open access journal
Neurobehavioral and Hematological Effects of Zapoteca portoricensis (Jacq.) H.M.Hern Root Ethylacetate Fraction against Scopolamine Induced Cognitive Impairment in Rats
By Felix Keneolisa Asogwa, Augustine Oluchukwu Asogwa, Daniel Lotanna Ajaghaku and 3 others.
Abstract
Background
Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by progressive dementia, neuroinflammation, and the accumulation of intracellular neurofibrillary tangles and extracellular amyloid plaques. Oxidative stress and cholinergic dysfunction are key contributors to cognitive decline in AD.