Emerging Trends in Pediatric Disease Management and Preventive Care: A Systematic Review

Child health systems are undergoing rapid transformation driven by biomedical innovation, digital integration, and strengthened preventive strategies.Over the past decade, advances in vaccination, pharmacological therapies, digital monitoring, artificial intelligence-assisted diagnostics, and school-based health programs have reshaped pediatric care delivery.Despite expanding technological capacity and structured prevention models, evidence remains fragmented across clinical, behavioural, and diagnostic domains.Long-term effectiveness, sustainability, and equitable implementation of emerging tools remain insufficiently synthesised within a unified framework.This systematic review synthesises contemporary evidence published between 2015 and 2025 to examine evolving approaches to pediatric disease management and prevention.A structured protocol guided database searches, study selection, and quality appraisal.Randomised controlled trials, cluster trials, feasibility studies, and diagnostic accuracy studies involving pediatric populations were included.Risk of bias was assessed using validated appraisal frameworks appropriate to the study design.Ten studies met the eligibility criteria.Interventions demonstrated measurable improvements in vaccine efficacy, respiratory infection reduction, obesity-related outcomes, injury prevention, asthma adherence, and diagnostic accuracy using artificial intelligence models.Digital and behavioural strategies showed promising trends, although long-term validation and scalability data were limited.These findings underscore the convergence of prevention-focused frameworks and technology-supported care models.Strengthening implementation strategies, harmonising outcome reporting, and prioritising equitable access will be essential for optimising future pediatric health systems.