Open access journal
Activity of esomeprazole and fluconazole against Aspergillus fumigatus and Candida albicans: An in vitro study
By Sachin T Jose.
Abstract
Background
Fungal infections caused by Aspergillus fumigatus and Candida albicans are a critical clinical challenge in immunocompromised individuals, and drug repurposing policies may improve the antifungal efficacy and overcome resistance.
Aim
This study assessed the interaction of esomeprazole and fluconazole in an in vitro experimental setting against eight clinical isolates of A. fumigatus and four clinical isolates of C. albicans.